Hormones

17-alpha-Estradiol

Evidence: Preclinical

Mechanism of Action

Non-feminizing estrogen that extends lifespan in male mice via metabolic improvements. Reduces hepatic mTOR signaling, improves glucose homeostasis, and reduces inflammation without estrogenic effects on reproductive tissues.

Interactions

  • Unknown human interaction profile

Contraindications

  • Not FDA-approved for human use
  • Theoretical hormone-sensitive cancer risk

Key Papers

  • Strong et al. 2016 - ITP lifespan extension data (Aging Cell)

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Disclaimer: This information is for educational purposes only and is not medical advice. BioAccelera Labs does not diagnose, treat, or prescribe. Consult a licensed healthcare provider before using any compound.

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