Supplements

Citrus Bergamot Extract

Evidence: Moderate-Strong

Mechanism of Action

Contains brutieridin and melitidin — statin-like HMG-CoA reductase inhibitors from bergamot orange. Activates AMPK, improves lipid profiles (reduces LDL, increases HDL), and has antioxidant effects. Supports cardiovascular and metabolic health.

Interactions

  • May potentiate statin effects (shared mechanism)
  • CYP3A4 inhibitor — caution with statin/drug interactions

Contraindications

  • Rhabdomyolysis risk if combined with high-dose statins without monitoring

Key Papers

  • Mollace et al. 2011 - Bergamot polyphenols and lipid lowering (Journal of Functional Foods)

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Disclaimer: This information is for educational purposes only and is not medical advice. BioAccelera Labs does not diagnose, treat, or prescribe. Consult a licensed healthcare provider before using any compound.

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