Supplements

Tributyrin (Butyrate Prodrug)

Evidence: Moderate

Mechanism of Action

Tributyrin is a triglyceride form of butyrate — a short-chain fatty acid critical for colonocyte health. HDAC inhibitor that supports gut barrier integrity, reduces intestinal inflammation, and modulates immune function. Superior absorption compared to sodium butyrate.

Interactions

  • Synergistic with probiotics and fiber
  • May enhance 5-ASA drugs for IBD

Contraindications

  • None established at standard doses

Key Papers

  • Donohoe et al. 2012 - Butyrate and colonocyte metabolism (Cell Metabolism)

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Disclaimer: This information is for educational purposes only and is not medical advice. BioAccelera Labs does not diagnose, treat, or prescribe. Consult a licensed healthcare provider before using any compound.

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